Micromechanical character of chain structure for biological tissue
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    Abstract:

    Objective A new method is used to describe the structure of biological tissue, and research the mechanical character of collagen fibre in the tissues. Methods A wormlike chain model is applied to capture the behavior of the collagen microfibrils. On the microlevel, the model used is basing on the statistics of long chain molecules; and on the macrolevel, the network of collagen chains is represented by a transversely isotropic eight chain unit cell introducing one characteristic material axis. Results At that event, the worm like chain model is chosen to analyse the mechanics character of biological tissue structure, and we get the force vs. elongation response curves of the wormlike chain model with anisotropy in an eight chain unit cell. Conclusion The eight chain unit cell has scaling and loading angle sensitivity. If the present model is governed by a limited number of physically motivated material parameters, it is believed to be ideally suited to simulate not only the passive behavior of soft biological tissues but also their active response to changes in the mechanical loading environment.

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. Micromechanical character of chain structure for biological tissue[J]. Journal of medical biomechanics,2007,22(4):403-406

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