Objective With considerion of aortic wall hyperelasticity and residual stress, to propose a numerical simulation method for predicting aortic blood pressure based on vascular compliance. Methods The residual stress solution method based on the closing opening angle was used to realizd the analytical solution for the pressure-radius relationship of the idealized double-layered aortic wall model. The vascular compliance was calculated, and the pressure-radius relationship was applied to the moving boundary representing the motion of the aortic wall for numerical simulation, to obtain the relationship between vascular compliance and pulse pressure. The effects of with or without residual stress, hyperelasticity or linear elasticity constitutive relationships, as well as different ages on vascular compliance and aortic blood pressure were compared. The function of the stent graft was incorporated, by considering the stented region as a rigid wall, simulating the effects of different stent numbers and stent positions on aortic blood pressure. Results Vascular compliance with residual stress was higher than that without residual stress; correspondingly, when residual stress was considered, aortic pulse pressure was slightly lower than that without residual stress. Compared to the linear elastic model, the hyperelastic model predicted a smaller aortic pulse pressure value. The vascular compliance for different age groups showed 40–49 year-old > 60–69 year-old > 70 year-old and above; correspondingly, the pulse pressure for different age groups showed 40–49 year-old < 60–69 year-old < 70 year-old and above. When a stent with 60 mm length was implanted in the aorta, as the number of stents increasing, the aortic pulse pressure continued to rise, indicating that the wider the range of stent implantation, the higher the pulse pressure. The closer the stent implantation site was to the heart, the higher the pulse pressure. Conclusions The proposed simulation method in this study can accurately predict blood pressure and evaluate aortic compliance, providing theoretical and technical support for stent design and surgical plan optimization.