【Abstract】 Objective In order to enhance the mechanical properties of trichiral honeycomb sandwich structures and to satisfy the design criteria for vertebral implant structures. Methods We constructed a chiral-like honeycomb sandwich structure with an auxiliary support structure for optimal design. We used the finite element method to study the influence of the auxiliary support structure on the chiral-like honeycomb sandwich structure and the relationship between the support position and the mechanical property indexes. Furthermore, we discussed the influence of the deformation mechanism of different structures on the mechanical properties. Results The results demonstrate that all chiral-like honeycomb sandwich structures exhibit enhanced mechanical properties in comparison to trichiral honeycomb sandwich structures. The most optimal chiral-like "d" _"CW" honeycomb sandwich structures are characterised by the presence of auxiliary support structures oriented perpendicular to the ligaments. Conclusion The mechanical properties of the chiral-like "d" _"CW" honeycomb sandwich structure with the auxiliary support structure positioned perpendicular to the ligament are optimal, and this position represents the optimal support position. When the volume is used as a control variable, the compressive stiffness, stiffness-to-mass ratio, and transverse strain of the chiral-like honeycomb sandwich structure in the x_1 direction are significantly correlated with the change of the support position, and all of them are positively correlated. As a novel chiral-like honeycomb structure, it provides a biomechanical basis for the optimal design and clinical application of honeycomb sandwich structures as vertebral implant structures. 【Keywords】 Chiral-like honeycomb sandwich structure; Auxiliary support structure; Structural optimization; Vertebral implant