Research in cellular mechanics has rapidly advanced in recent years, uncovering how cells regulate their functions and behaviors by sensing and responding to mechanical cues from their environment. In 2023, significant breakthroughs were made in understanding the mechanical properties of cells, their mechanosensing of solid and fluid environments, and their adaptability under dynamic mechanical conditions. Meanwhile, advanced measurement techniques and mechanical models have provided new tools for investigation. These achievements have deepened the understanding of physiological and pathological processes, offering new approaches for disease diagnosis, prevention, and intervention. This review summarizes the research progress by Chinese scholars in cellular mechanics and explores the mechanical mechanisms exhibited in various biological processes in the year 2023.