Objective To analyze and compare the strength of titanium alloy crystalline porous scaffolds and porous scaffolds with a triply periodic minimal surface (TPMS) structure and explore the effect of porosity on the equivalent elastic modulus and permeability. Methods Crystalline porous scaffolds (cell 1-4) and TPMS porous scaffolds (P-, G-, D-, and FKS-type) with The same porosity were constructed, and the equivalent elastic modulus, equivalent yield strength, and permeability of the scaffolds were calculated using finite element simulation. Results The elastic modulus of eight scaffolds was in the range of 5.1－10.4 GPa, the yield strength was in the range of 69－110 MPa, and the permeability of 4 crystalline scaffolds was in the range of 0.015－0.030 mm2. Conclusions With an increase in porosity, the elastic modulus and yield strength of the scaffold gradually decreased, and the permeability gradually increased. The cell 2-type scaffold is suitable for repairing defects at load-bearing bone sites because of its high elastic modulus and yield strength. The cell 3-type scaffold with a uniform stress distribution and a longer linear elasticity phase may be suitable for designing porous tibial platforms for knee joint prostheses.