Spine is one of the most important skeletal structures in human body. It has the function of protecting the spinal cord, supporting body weight, slowing impact and allowing flexible movement of the trunk. The study of spinal biomechanics is very important for a comprehensive understanding of the structure and function of the spine and the pathogenesis of diseases. In 2023, scholars at home and abroad have done a lot of researches on spine related biomechanics, including the cognitive aspects on basic biomechanics of the spine, the changes in mechanical properties of the spine under pathological conditions, and the design of various treatment methods of spinal diseases based on biomechanical researches. This review focuses on the research progress of spinal biomechanics, and introduces several typical spinal diseases or pathological states as examples.