The relationship between left ventricular end-systolic biomechanical changes and diastolic heart failure
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1.Baotou Medical College Second Affiliated Hospital;2.Inner Mongolia Medical University

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    Abstract:

    Objective In terms of the relations among maxEav、Emax and E/A value in patients with essential hypertension, the study is suppose to explore the maxEav and Emax is is direct biomechanical indexes for evaluating myocardial diastolic function,and biomechanical mechanism of diastolic heart failure. Methods (1) 298 patients with essential hypertension were selected as the research object in the Second affiliated hospital of baotou medical college . The groups were examined by conventional three-dimensional echocardiography. The difference was statistically significant. Results (1) Correlation analysis between maxEav,Emax and E/A value of the five groups①The maxEav of the LVCH group was significantly negatively correlated with the E/A value (r=- 0.417, P< 0.01).②The maxEav and E/A value of the LVCH group were significantly negatively correlated (r=-0.366, P<0.05),the Emax of the LVCH group was significantly negatively correlated with the E/A value (r=- 0.491, P<0.01).③The maxEav was significantly negatively correlated with E/A value in the LVCR group (r=-0.404, P<0.01),the Emax and E/A value in the LVCH group Significant negative correlation (r=-0.235,P<0.05).(2) The difference of E/A value between LVCR group, LVCH group and control group was P<0.05, the difference was statistically significant, and the difference of E/A value between the other groups was P>0.05. The maxEav,Emax and E/A of the eccentric hypertrophy group were significantly increased compared with the other groups, the difference was statistically significant (P<0.05); (3) Compared with the control group, The maxEav and Emax of each group of hypertension decreased, and the difference was statistically significant (P<0.05). The difference was statistically significant. Conclusion Analysis of maxEav and Emax is a more sensitive and simple index for judging left ventricular diastolic function. Simultaneous analysis of changes in myocardial maxEav,Emax in patients with left ventricular remodeling and diastolic dysfunction The pathogenesis of diastolic heart failure provides a theoretical basis for the prevention and treatment of diastolic heart failure in the future.

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History
  • Received:February 03,2020
  • Revised:February 25,2020
  • Adopted:February 27,2020
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