Abstract:The occurrence, development, diagnosis and therapy of cancer all involve complicated coupling and interplay of mechanical, physical, chemical, and biological cues. Tumor biomechanics is not only of vital significance for understanding these biological processes, but also provides strong support to many clinical issues related to cancer. This review briefly introduces the stateoftheart of tumor biomechanics, especially the advances achieved by Chinese scholars in the areas of cancerous cells and tissues, including experimental and theoretical studies on the interaction between cancerous cells and extracellular matrix, the angiogenesis and growth of tumors.