Objective To construct and validate the 95th percentile finite element model of Chinese human head, evaluate the relative displacement between the skull and brain according to four types of skull brain relative displacement experiments as references, and investigate the shear strain distributions on the brain. Methods By comparing the relative displacement curve derived from the experiment and simulation and referring to conclusions from animal and physical experiments, the position of higher shear strain was investigated. Results High correlations could be found between the simulated and experimental results for skull brain relative displacement. Peaks and troughs could always appear in curves of skull brain relative displacement due to the fact that the brain tissue tended to return to its initial state. The results that higher strain could occur at temporal lobe of the brain, corpus callosum and brain surface were consistent with conclusions from the animal and physical experiments. ConclusionsT he 95th percentile finite element model of Chinese human head is validated with good biofidelity. Due to the rotational motion of human head, higher shear strain will occur on brain surface and in deep brain, leading to injuries, which provids a scientific theoretical basis for the study on injury mechanism of human head in traffic accidents.