Objective To analyze the interrelation between fat distribution feature inside vertebrae and its biomechanics feature through observing fat distribution feature inside vertebrae of health adult and associated it with the researched results of biomechanics feature of vertebral. Method This study include 56 health adult’s MR imaging material of T11- L5,we divided every vertebrae into 16 area, observed and noted the signal intensity of every area, made statistical analysis to the incidences of hyper-intensity signal among different area. At last, compare the study results to the biomechanics feature inside vertebrae researched. Results The incidences of hyper-intensity signal in different area are obviously different, it is the highest in Pedicle of vertebral arch (98%); the incidence in marginal (92%) is higher than it in intermedius (69%) in post-superior border, but the incidence in intermedius (50%) is higher than it in marginal (9%) in post-inferior border, there is no hyper-intensity signal distribution in anterior border and a few of signal distribution under end-plate (16%). The results of statistics analysis showed the difference of incidence in different area have obviously significance except it between the marginal in post-inferior border and under end-plate (P>0.0033). Conclusion The incidences of hyper-intensity signal in pedicle of vertebral arch and in post-superior border are obviously higher than other areas in vertebrae, both area bear the greatest stress in vertebrae according to the biomechanics study results.