It is a trend for biomechanics development of spinal internal fixation device in the furture that how to attain fast fixation and retain maxiumum spinal movement function. The research and design of artificial anlanto-odontoid joint will be a feasible technique, which can not only rebuild the stability of atlanto-axial joint, but also reserve the rotation function between atlas and axis. This paper reviewed recent advancements on the biomechanics study of artificial anlanto- odontoid joint, with the focus on its design requirements and principles, implant feasible analysis and implant indication etc.