Objective Three-dimensional digital structure modeling of human perfused blood vessels for anatomyteaching and virtual clinic surgery. Methods High-resolution and color cryo-sections datasets were acquired withperfused arteries on the Visual Chinese Human Male-No.1. To make the images of datasets dimensional registered and theblood vessel was segmented and classified interactively. The segmented data was reconstructed with parallelismalgorithm. Result The three-dimension structure models of the arteries, veins and heart were established. The modelsof the whole cardiovascular system of Visual Chinese are integrity and real represented for blood vessels perfusion.Conclusion Based on the high-resolution images of VCH cryo-sections and perfusion of artery, the integrity andaccurate human blood vessel models has been constructed.