A Study of Blood Flows in Left Coronary Artery and Their Dependences on Perfusion Pressure with Modeling and Simulation
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    Abstract:

    Objective A circuit model of left coronary artery was created to analysis the theory of external counterpulstion (EECP) enhanced perfusion blood flow of ischemic myocardium. Methods From Newton's equation and the continuity equation, an equivalent analogue circuit model can be derived for each small segment of the coronary arteries. By replacing each segment with its analogue circuit model, a final model of left coronary artery can be constructed. Using Pspice simulation software, The model was simulated using experimentally measured aortic pressure. Results The model simulation shows that perfusion blood flow through left coronary artery were increased obviously with augmentations of perfusion pressure by EECP during diastolic period. Conclusion The results demonstrate that raising perfusion pressure with EECP can improve perfusion blood flow in left coronary artery.

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WANG Dong-cheng, WANG Huai-yang, WU Xiao-ming, CEN Ren-jin. A Study of Blood Flows in Left Coronary Artery and Their Dependences on Perfusion Pressure with Modeling and Simulation[J]. Journal of medical biomechanics,2004,19(1):15-18

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