Objective:To evaluate the efficacy of BSYJF on raising the quality of cacellous bone of vertebrate in osteoposrotic rat model induced by ovariectomy and to inquiry into the mechanism on improving biomechanical propelties of cancellous bone. Method:Forty 12-month-old female Wistar rats were divided randomizedly into four groups:Sham control group,Ovx contral group,BSYJF group(Ovx+BSYJF) and BML group(Ovx+BML). After sacrifice, biomechanical parameters and other parameters of No.2 lulmbar vertebrate were determined. Results:The macroscopic geometry structure(height and volume) in Ovx control group, BSYJF group and BML group were not altered siguificantgroup were reduced by 11% (p<0.05) and 6% (p >0.05 ),respectively vs Sham control group. In comparison with those Of Ovx control group,the BMD and the BCD in BSYJF group were increased by 3% (p<0.05) and 8% (p> 0.05),and the BMD and the BCD in BML group were increased by 9% (p<0.05) and 12% (p>0.05).The mechanical parameters in Ovx control group were all decreased significantly (p<0.05),respectively vs Sham control group.Especially,in elastic phase,the mechanical parameter in BSYJF group were increased significantly (p <0.05 ),vs Ovx control group;but those in BML group were not increased significantly (p >0. 05 ),vs Ovx control group. In plastic phase,the mechanical parameters were increasedsignificantly,respectively vs Ovx control group.Conclusion:BSYJF can not only raise the quality of cancellous bone of vertebrate in the rat model induced by ovariectomy,but also have superiority to BML in improving the cancellous bone mechanical property in elastic phase.