The purpose of this study is to Investigate the effects of management on fatigue equation of skeletalmuscle after 7days continuous eccentric exercise. We estrablished continuous eccentric exercisemodels on rabbits lower-limbs and human elbow flexor muscles with specially designed equipment.Meanwhile, abservation was made on the management of manipulation, stretch, water bath, saltwarm bath, fumigant and lotion applived to the muscles livalved after exercise program. The resultsof fatigue equations of top work, top toque, mean toque and total work showed that manipulation,stretch, fumigant and lotion could effectively, relieve musslar fatigue.