李建军,罗七一,谢志勇,李雨.冠脉支架的疲劳寿命分析[J].医用生物力学,2010,25(1):68-73
冠脉支架的疲劳寿命分析
Fatigue Life Analysis of Coronary Stent
  
DOI:10.3871/j.1004-7220.2010.01.73.
中文关键词:  脉动载荷  有限元  Goodman准则  疲劳寿命  加速疲劳
英文关键词:Pulsatile loading  Finite element  Goodman criteria  Fatigue life  Accelerated fatigue
基金项目:
作者单位
李建军 微创医疗器械(上海)有限公司 
罗七一 微创医疗器械(上海)有限公司
上海理工大学医疗器械与食品学院 
谢志勇 微创医疗器械(上海)有限公司 
李雨 微创医疗器械(上海)有限公司 
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中文摘要:
      目的 冠脉支架植入后,在血管周期脉动载荷作用下,要求至少经过相当于10年约4亿次的循环后保持完整,维持其预期功能,需要评价其疲劳性能。方法 使用有限元方法分析了支架在使用过程中的应力分布,根据Goodman准则评价了支架的疲劳寿命,同时采用加速疲劳对支架进行疲劳试验。结果 分析发现最危险点始终位于支架弯折位置侧内表面区域。结论 结果表明有限元分析可以很好的模拟支架的疲劳特性,为支架的设计提供理论指导。
英文摘要:
      Abstract Objective After the implantation, coronary stent was expected at least to keep integrity and maintain the predicated function for over 10 years or 4e8 cycles under the pulsatile loading conditions, and the fatigue property of the stent should be evaluated. Method The finite method was used to analyze the stress distribution of different phases and evaluate the fatigue life according to Goodman criteria, meanwhile, the accelerated fatigue experiment was also performed . Results It could be concluded that the dangerous points were located in the lateral inner surface of stent curvature. Conclusion The results proved that the fatigue property could be simulated through the finite element analysis, which can provide the theoretical guidance for the stent design.
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