In active health, biomechanics plays an irreplaceable role. Exercise creates mechanical stimulation to human tissues and organs. It promotes health, or causes injury and disease. In addition, biomechanics is involved in the design and evaluation of assistive devices, as well as in rehabilitation clinical diagnosis and treatment. The development of active health biomechanics requires the integration of sports and medicine. It includes more dynamics, fatigue and mechanical coupling issues. In the future research, on the one hand, the experience of other directions in biomechanics should be learnt from. On the other hand, it is necessary to combine the frontiers of scientific and technological development to develop new directions in biomechanics.