丛梦杨,赵慧慧,许星明,代顺,陈传智,邱建峰,钱秀清,秦升学.右冠状动脉起源于左冠状窦的血流动力学分析[J].医用生物力学,2020,35(3):284-288
右冠状动脉起源于左冠状窦的血流动力学分析
Hemodynamic Analysis on Anomalous Origin of the Right Coronary Artery from the Left Coronary Artery Sinus
投稿时间:2019-05-15  修订日期:2019-06-27
DOI:
中文关键词:  右冠状动脉  左冠状窦  血流动力学  血流速度  压力  壁面剪切力
英文关键词:right coronary artery (RCA)  left coronary artery sinus  hemodynamics  flow velocity  pressure  wall shear stress (WSS)
基金项目:山东省泰山学者项目(ts201712065)
作者单位
丛梦杨 山东科技大学 机械电子工程学院 
赵慧慧 山东第一医科大学(山东省医学科学院) 放射学院
山东第一医科大学(山东省医学科学院) 医学工程技术中心 
许星明 山东科技大学 机械电子工程学院 
代顺 上海交通大学医学院附属同仁医院 影像科 
陈传智 上海市东方医院 医学影像科 
邱建峰 山东第一医科大学(山东省医学科学院) 放射学院
山东第一医科大学(山东省医学科学院) 医学工程技术中心 
钱秀清 首都医科大学 生物医学工程学院 
秦升学 山东科技大学 机械电子工程学院 
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中文摘要:
      目的 通过计算流体动力学(computational fluid dynamics, CFD)分析右冠状动脉起源于左冠状窦(anomalous origin of the right coronary artery from the left coronary artery sinus, AORL)的血流动力学参数,从而有效评估疾病。方法 选取正常右冠状动脉(right coronary artery, RCA)和AORL两例个体病例,在Mimics软件中重建两个病例的血管模型,并将模型导入ANSYS CFX软件中进行血流动力学模拟计算,比较正常和AORL两种模型的血流动力学情况。结果 AORL模型右冠状动脉入口截面具有较小的血流量(9.35 cm3/s),有可能会导致右冠状动脉下游供血不足;AORL模型右冠状动脉急性拐角处的压力(13.78 kPa)相比于正常模型右冠状动脉(14.9 kPa)较低;AORL模型壁面剪切力(12.83 Pa)大于正常模型(9.74 Pa);AORL模型血管壁变形量较大。结论 AORL入口流速及拐角处压力均比正常RCA小,从而可能导致缺血症状发生。研究结果对临床上有效评估缺血等疾病具有理论指导意义。
英文摘要:
      Objective To analyze the hemodynamic parameters of anomalous origin of the right coronary artery from the left coronary artery sinus (AORL) based on computational fluid dynamics (CFD), so as to make an evaluation of the disease. Methods A normal right coronary artery (RCA) case and an AORL case were selected. Two models were reconstructed in Mimics software and imported into ANSYS CFX software for hemodynamics simulation. The hemodynamics of normal RCA model and AORL model were compared. Results AORL model had a smaller volume flow (9.35 cm3/s), which might lead to insufficient blood supply downstream of the RCA; the pressure at the acute corner of AORL model (13.78 kPa) was lower than normal RCA model (14.9 kPa); the wall shear stress (WSS) of AORL model (12.83 Pa) was larger than that of normal RCA model (9.74 Pa); the total deformation of AORL model was relatively large. Conclusions The entrance velocity and pressure of AORL were lower than those of normal RCA, which might lead to ischemic symptoms. The research findings are of theoretical significance for the effective evaluation of ischemia and other diseases in clinic.
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