许刚,门玉涛,王鑫,张春秋.缺损关节软骨在循环压缩载荷下棘轮行为的实验研究[J].医用生物力学,2019,34(5):529-535
缺损关节软骨在循环压缩载荷下棘轮行为的实验研究
Experimental Study on Ratcheting Behavior of Defective Cartilage under Cyclic Compressive Loading
投稿时间:2018-08-09  修订日期:2018-09-28
DOI:
中文关键词:  关节软骨  循环载荷  棘轮行为  力学性能
英文关键词:articular cartilage  cyclic loading  ratcheting behavior  mechanical properties
基金项目:天津市自然科学基金项目(18JCYBJC95200,18JCZDJC36100,17JCYBJC41100),国家自然科学基金项目(11402171,11672208,11432016)
作者单位
许刚 天津理工大学 机械工程学院 天津市先进机电系统设计与智能控制重点实验室机电工程国家级实验教学示范中心 
门玉涛 天津理工大学 机械工程学院 天津市先进机电系统设计与智能控制重点实验室机电工程国家级实验教学示范中心 
王鑫 天津理工大学 机械工程学院 天津市先进机电系统设计与智能控制重点实验室机电工程国家级实验教学示范中心 
张春秋 天津理工大学 机械工程学院 天津市先进机电系统设计与智能控制重点实验室机电工程国家级实验教学示范中心 
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中文摘要:
      目的 研究缺损软骨在循环压缩载荷下的棘轮应变行为,探索缺损关节软骨的损伤演化规律。方法 取新鲜的成年猪股骨远端关节软骨,对不同缺损深度软骨试样进行不同参数的三角波循环加载。结合非接触式数字图像技术,获得软骨不同层区的棘轮应变。结果 随循环加载圈数的增加,软骨各层棘轮应变均表现为先急剧增大,然后缓慢增加并趋于平稳,由浅层到深层棘轮应变逐渐减小。各层区对循环圈数响应不同,浅层在50圈内应变增加较快,中层在100圈内应变增加较快,深层在75圈内应变增加较快。除了中层区域响应有滞后性,浅层、深层的棘轮应变与应力幅值、缺损深度呈正相关,与加载速率呈负相关。结论 软骨的棘轮行为受软骨的特殊结构的影响,缺损使软骨各层区的应变增大,易造成损伤加剧。实验结果 为组织工程软骨的构建提供参考依据。
英文摘要:
      Objective To study the ratcheting behavior of defective cartilage under cyclic compressive loading, so as to explore the pattern of damage evolution for defective articular cartilage. Methods Fresh articular cartilage was obtained from the distal femur of adult porcine, and the cartilage samples with different depth of defect were applied under triangular wave cyclic loading with different parameters. Combined with non-contact digital image technology, the ratcheting strain at different layers of cartilage was obtained. Results With the increase of loading cycles numbers, the ratcheting strain at each layer of cartilage increased sharply at first, then increased slowly and tended to be stable, and the ratcheting strain decreased gradually from shallow layer to deep layer. The response of each layer to cycle number was different. The strain in shallow layer increased rapidly within 50 cycles, while the strain in middle layer increased rapidly within 100 cycles and the strain in deep layer increased rapidly within 75 cycles. The ratcheting strain in shallow and deep layers was positively correlated with the stress amplitude and defect depth, and negatively correlated with the loading rate, while hysteresis response occurreds in middle layer. Conclusions The ratcheting behavior of cartilage was affected by special structure of the cartilage. The defect caused the strain increasing in each layer of cartilage, which could easily result in the aggravation of damage. The experiment results provide references for the construction of tissue-engineered cartilage.
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