基于流固耦合的载瘤血管内血液流动及血管损伤分析
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Analysis of Blood Flow and Vascular Injury in Aneurysm-Carrying Vessels Based on Fluid-Structure Interaction Method
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    摘要:

    目的 研究两种常见血管瘤内的血液流动及其对血管壁力学性能的影响,以期提高动脉瘤的诊治水平、改善患者的预后。方法 应用流固耦合方法 对两种常见动脉瘤载瘤血管与血液之间的相互作用进行基于有限元计算的研究。主要分析瘤内血液流速、瘤壁变形、载瘤血管的应力分布和破坏形式。结果 两种瘤内血液流速都很低而且流动平稳,使得瘤内可以形成较好的沉积和附着条件。瘤与血管下游的交界处是破坏的危险位置,梭形动脉瘤会在该处外壁发生剪切破坏,而囊形动脉瘤会在该处内壁发生拉伸破坏。在相同的血液流动作用下,囊形动脉瘤的载瘤血管会出现更大的应力,故更容易发生破坏,而且拉伸破坏会导致更严重的后果。结论 动脉瘤与血管结合处易发生破坏;囊形动脉瘤危险性高、危害大。

    Abstract:

    Objective To study the blood flow in aneurysm and its influence on mechanical properties of vascular walls for two kinds of common aneurysms, so as to improve the diagnosis and treatment of aneurysms and the prognosis of patients. Methods The interaction between the aneurysm-carrying vessels and blood of two common aneurysms was studied by fluid-structure interaction method. The blood flow velocity, wall deformation, stress distribution and damage form of aneurysm-carrying vessels were analyzed. Results The blood flow in both aneurysms were slow and stable, which resulted in better deposition and adhesion conditions. The junction between the aneurysm and the downstream of the blood vessel was a dangerous place for damage. The spindle aneurysm would undergo shear failure on outer wall of the aneurysm, while the cystic aneurysm would undergo stretching failure on inner wall. Under the effect of the same blood flow, a larger stress appeared on the cystic aneurysm, which was more prone to damage, and the tensile failure would lead to a more serious consequences. Conclusions The junction at the aneurysm and blood vessel is prone to damage, and the cystic aneurysm is more dangerous and harmful.

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韩嘉玮,胡义锋.基于流固耦合的载瘤血管内血液流动及血管损伤分析[J].医用生物力学,2019,34(4):372-378

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  • 收稿日期:2018-06-13
  • 最后修改日期:2018-08-23
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  • 在线发布日期: 2019-08-28
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