彭坤,乔爱科.新型可降解锌合金支架的结构设计及其力学性能分析[J].医用生物力学,2019,34(2):160-165
新型可降解锌合金支架的结构设计及其力学性能分析
Structure Design and Mechanical Analysis of a Novel Biodegradable Zinc Alloy Stent
投稿时间:2018-12-17  修订日期:2019-02-02
DOI:
中文关键词:  生物可降解支架  结构设计  力学性能  有限元分析
英文关键词:biodegradable stent  structure design  mechanical performance  finite element analysis
基金项目:国家自然科学基金项目(11772015),北京市教委科技计划重点项目,北京市自然科学基金B类项目(KZ201710005007)
作者单位
彭坤 北京工业大学 生命科学与生物工程学院 
乔爱科 北京工业大学 生命科学与生物工程学院 
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中文摘要:
      目的 对比分析一款新结构可降解支架和传统结构可降解支架力学性能和对狭窄血管的治疗效果。方法 利用有限元数值模拟,将新结构支架和传统结构支架分别植入直径狭窄为30%的血管,对比分析两种支架的支撑性能及其对狭窄血管重构的影响。结果 与传统结构支架相比,新结构支架的径向回弹率和狗骨头率分别降低了26.6%和34.7%。此外,植入新结构支架的狭窄血管回弹较小,拥有更平滑更大的管腔。结论 对比传统结构支架,新结构支架具有更高的支撑性能,对狭窄血管的治疗效果更佳。具有高支撑性能的新结构支架有望成为临床介入治疗设备的新选择。
英文摘要:
      Objective To compare and analyze the mechanical performance of a new biodegradable stent and a common stent and their effects on treating the stenotic vessels. Methods Using finite numerical simulation, the new stent and the common stent were implanted into vessels with a diameter stenosis of 30%, and their support performance and influences on reshaping the stenotic vessels were investigated. Results The radial recoiling ratio and dog-boning ratio of the new stent were decreased by 26.6% and 34.7%, respectively, compared with the common stent. Besides, the stenotic vessel deployed with the new stent recoiled less and had a flatter and larger lumen. Conclusions Compared with the common stent, the new stent has stronger scaffold performance and a better therapeutic effect on stenotic vessels. The new stent with stronger scaffold performance is highly expected to be an alternative choice in interventional surgeries.
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