As an effective implant for bone fracture, bone screws are widely used in clinic. Based on the clinical application of bone screws, this study summarized different kinds of bone screws according to their structures and materials, analyzed 3 kinds of common screw failure (loosening, breaking, corrosion) and the influencing factors. The common testing methods of screws were summarized, especially the key points and difficulties during the testing process for bone screws were analyzed, which was important for improving the design of product, selection of materials and development of in vitro testing technology. The development trend for testing method of bone screws was prospected as well.