目的 研究维医沙疗对人体股动脉分叉血管血流动力学及受力的影响，进而揭示维医沙疗对人体股动脉血栓成因的作用机制。方法 在室内维医沙疗系统中对受试者进行维医沙疗，用飞利浦便携式彩色多普勒超声诊断仪分别测试受试者维医沙疗前后的股动脉血流速度峰值、内径和阻力指数(resistant index,RI),并进行统计学分析；重构股动脉分支的三维流-固耦合有限元模型，采用ANSYS workbench模拟计算维医沙疗前后流场的血流速度、压力、壁面切应力和股动脉壁的应力、应变、总位移。结果 维医沙疗后股动脉血流速度峰值的平均值和内径分别增大了32.43%和2.63%，RI降低了4.88%，股动脉血流速度峰值和RI维医沙疗前后差异均具有统计学意义（P<0.05），股动脉内径维医沙疗前后差异没有统计学意义（P>0.05）。维医沙疗后股动脉血流速度、压力和壁面切应力最大值分别增大29.91%、68.52%和46.55%;维医沙疗后股动脉壁的总位移、应力和应变最大值分别增大65.85%、45.45%和44%。结论 维医沙疗对加快血流速度、降低RI有显著影响，能增大股动脉血管内径，从而改善股动脉内血液的循环；并且维医沙疗后股动脉壁面切应力、血流速度、压力以及股动脉壁所受应力、应变和总位移有所增大，分叉处的高压力区域有所减少，维医沙疗对降低股动脉粥样硬化及血栓形成有一定的积极作用。

Objective To study effects from sand therapy of Uyghur medicine on hemodynamics in femoral artery branch and stress, so as to further discuss the functions and mechanisms of Uyghur sand therapy for treatment of femoral artery thrombosis formation. Methods Uyghur sand therapy was conducted on the subjects by indoor Uyghur sand therapy system. The peak values of blood flow velocity, inner diameter and resistance index (RI) of femoral artery before and after receiving Uyghur sand therapy were measured by the ultra-portable Doppler Diagnostic Ultrasound System for statistic analysis. Three-dimensional fluid-solid coupling model of femoral artery branch was reconstructed, and blood flow velocity, pressure, wall shear stress in the flow field as well as the equivalent stress, strain, total displacement on femoral artery wall were simulated and analyzed by the ANSYS Workbench. Results After receiving Uyghur sand therapy, the mean peak values of blood flow velocity and inner diameter of femoral artery increased by 32.43% and 2.68%, while the mean values of RI decreased by 4.88%, which showed it had the statistical difference(P<0.05).But no statistical difference was found in the inner diameter with or without Uyghur sand therapy (P>0.05).Besides, the maximum values of blood flow velocity, pressure and wall shear stress increased by 29.91%，68.51%,46.54%,respectively, while the maximum values of equivalent stress, equivalent strain, total displacement on femoral artery wall increased by 65.85%，45.45%，44%, respectively, after receiving Uyghur sand therapy. Conclusions Uyghur sand therapy can increase blood flow velocity and decrease RI obviously，and help to expand the inner diameter of femoral artery to make blood circulation inside improved. With Uyghur sand therapy, the shear stress, blood flow velocity, pressure as well as the stress, strain, total displacement on femoral artery walls also increase, meanwhile，high pressure area on femoral artery branch reduces to some extent, which shows it plays a certain positive role in reducing atherosclerosis and thrombus formation inside femoral artery.

国家自然科学基金项目（31460245,81160458），新疆维吾尔族自治区自然科学基金项目（2014211A005）