腹主动脉瘤的数值计算模型比较研究
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江苏省自然科学基金项目(BK2010405), 教育部博士点基金项目(20110092120037)


Comparison between computational models of abdominal aortic aneurysm
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    摘要:

    目的 分别采用纯流体模型和流固耦合模型来计算腹主动脉瘤的血流动力学特征,比较两种数值模型的不同,并讨论在研究腹主动脉瘤中的应用。方法 使用Gambit 2.2.30和COMSOL Multiphysics 4.2建立腹主动脉瘤的理想模型,分别基于有限体的方法分析纯流体模型,基于任意拉格朗日 欧拉算法(Arbitrary Lagrangian-Eulerian)计算流固耦合模型。结果 同样的入口速度下,纯流体模型出现4个涡流和6个局部压力集中;流固耦合模型只有2个涡流和局部压力集中,且涡流中心更接近腹主动脉瘤的远端。在边界层分离点、血流回帖位置以及腹主动脉瘤的近端和远端,两种模型均出现壁剪切力极值。血管壁的最大形变和最大壁应力出现在腹主动脉瘤的近端和远端。结论 两种模型的涡流个数和涡流中心的位置均不一样,与瘤体的生长有着密切的关联;流固耦合模型中的最大壁剪切力比纯流体模型要小36%;最大壁应力和最大血管壁的形变量与出口血压呈正相关。在研究血管瘤生长与血流动力学的关系时需要考虑使用流固耦合模型。

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    Objective To compare the differences in the hemodynamic parameters of abdominal aortic aneurysm (AAA) between fluid-structure interaction model (FSIM) and fluid-only model (FM), so as to discuss their application in the research of AAA. MethodsAn idealized AAA model was created based on patient-specific AAA data. In FM, the flow, pressure and wall shear stress (WSS) were computed using finite volume method. In FSIM, an Arbitrary Lagrangian-Eulerian algorithm was used to solve the flow in a continuously deforming geometry. The hemodynamic parameters of both models were obtained for discussion. Results Under the same inlet velocity, there were only two symmetrical vortexes in the AAA dilation area for FSIM. In contrast, four recirculation areas existed in FM; two were main vortexes and the other two were secondary flow, which were located between the main recirculation area and the arterial wall. Six local pressure concentrations occurred in the distal end of AAA and the recirculation area for FM. However, there were only two local pressure concentrations in FSIM. The vortex center of the recirculation area in FSIM was much more close to the distal end of AAA and the area was much larger because of AAA expansion. Four extreme values of WSS existed at the proximal of AAA, the point of boundary layer separation, the point of flow reattachment and the distal end of AAA, respectively, in both FM and FSIM. The maximum wall stress and the largest wall deformation were both located at the proximal and distal end of AAA. Conclusions The number and center of the recirculation area for both models are different, while the change of vortex is closely associated with the AAA growth. The largest WSS of FSIM is 36% smaller than that of FM. Both the maximum wall stress and largest wall displacement shall increase with the outlet pressure increasing. FSIM needs to be considered for studying the relationship between AAA growth and shear stress.

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史正涛,李志勇.腹主动脉瘤的数值计算模型比较研究[J].医用生物力学,2012,27(5):495-500

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  • 收稿日期:2012-08-01
  • 最后修改日期:2012-08-15
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