多孔生物陶瓷与PVA水凝胶复合材料的制备与力学性能分析
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江苏省自然科学基金项目(创新学者攀登计划项目)(BK2008005)


Preparation and mechanical properties analysis of porous biological ceramics and PVA hydrogel composite material
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    摘要:

    目的 将多孔生物陶瓷和聚乙烯醇(PVA)水凝胶交联成为一个仿生软骨 硬关节双层结构,并对该结构的微观形貌和力学性能进行分析。方法 以羟基磷灰石(HA)为基体,采用添加碳酸氢铵(NH4HCO3)晶粒造孔的方式制备不同孔隙率的多孔羟基磷灰石生物陶瓷,以聚乙烯醇(PVA)为主要原料,环氧丙烷为交联剂,在多孔生物陶瓷表面及基体内交联制备出PVA水凝胶形成双层结构,对试样的断口形貌进行表征,对试样的拉伸强度和剪切强度等性能进行测试分析。结果 交联的PVA水凝胶可以渗入到生物陶瓷基体表层以下的孔隙中,并且陶瓷基体和PVA水凝胶有很好的结合。随着多孔生物陶瓷孔隙率的增大,试样的最大拉伸和剪切负载均增大,平均孔隙率为70%试样的最大拉伸和剪切负载分别为153.61 N和64.46 N;而相应的拉伸和剪切强度略有下降,平均孔隙率为30%试样对应的最大拉伸和剪切强度分别为2.12 MPa和1.13 MPa。两者的失效形式均是因为裂纹的扩展,断口的微观形貌表明,断裂面存在明显的裂纹和内部缺陷,同时可观察出裂纹源和扩展方向。结论 考虑到多孔生物陶瓷基体的强度,平均孔隙率为50%的多孔生物陶瓷的渗入效果适中,试样的拉伸强度和剪切强度、多孔生物陶瓷基体的压缩强度也有一定的保证,选择孔隙率为50%的试样较为合适。

    Abstract:

    Objective To cross-link the porous biological ceramics and PVA hydrogel to form a double layer construction between the artificial cartilage and hard joint, and to analyze its morphologies and mechanical properties. Methods With hydroxyl apatite (HA) as the substrate, the porous hydroxyl apatite biological ceramics with different porosities were prepared by using NH4HCO3 crystal grains as the pore-formed material. The poly vinyl alcohol (PVA) and epoxypropane were used as the primary material and cross-linking agent, respectively. The PVA hydrogel with double layer construction was cross-linked and prepared on the porous biological ceramics surface. The fracture appearances of the test specimen section were characterized. The performances of anti tensile strength and anti-shear strength for PVA hydrogel were analyzed. Results The cross-linked PVA hydrogel could permeate in the biological ceramics substrate, and the union between ceramic substrate and PVA hydrogel performed well. With the porosity of the porous biological ceramics increasing, the tension load and shear load of the PVA hydrogel samples both increased, and with the average porosity of 70%, the samples’ biggest tension load and shear load were 153.61 N and 64.46 N, respectively. But the corresponding tensile strength and shear strength both decreased and with the average porsity of 70%, the samples’ biggest tensile strength and shear strength were 2.12 MPa and 1.13 MPa, respectively. The failure mode of both tension and shear tests for PVA hydrogel samples was due to the crack propagation, and the fracture morphologies showed that obvious cracks and internal defects appeared on the fracture surface, while the source of the crack and the direction of the crack propagation could be observed. Conclusions Considering the compression strength of porous biological ceramics, the permeation effect on the porous biological ceramic substrate with the average porosity of 50% is moderate to be used, which ensures the appropriate shear and tensile strength of PVA hydrogel samples and the compression strength of porous biological ceramic.

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刘金龙,张德坤,葛世荣.多孔生物陶瓷与PVA水凝胶复合材料的制备与力学性能分析[J].医用生物力学,2011,26(4):341-348

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  • 收稿日期:2011-01-25
  • 最后修改日期:2011-03-04
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