Cytoskeleton can cause active deformations and resist passive deformations which related to some active deformations of cells known as mitosis. Mitosis occurs through a series of stereotypical shape changes resulted in the mechanical separation of a mother cell into two daugther cells, accompanied by mechanical phenomena throughout the whole course. As a molecular motor of cytoskeleton, myosin II is a kind of multifunctional protein that can participate in mitosis. To make deep study on the roles of myosin II in mitosis could get important theoretical and application value. This paper will sum up the recent research achievements on roles of myosin II in mitosis.