新型钛合金人工腰椎间盘的生物力学研究
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Biomechanical evaluation of a new titanium alloy artificial lumbar intervertebral disc
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    摘要:

    目的研制一种新型钛合金人工腰椎间盘并评价其生物力学特点。方法设计一种新型两部件球窝关节人工腰椎间盘,使用新型低弹性模量钛合金(50GPa)制造,应用生物材料试验机分别进行压缩刚度、扭转刚度、疲劳强度生物力学检测。结果新型钛合金人工腰椎间盘具有前屈、后伸、左右侧弯功能。压缩刚度为不锈钢的1/3,约为50~66.7GPa;扭转刚度为388.54N·m/(°);经过1×107次反复压缩疲劳测试,并未发生明显的变形及损坏。比较测试前、100、200、500、1000万次疲劳测试后压缩刚度没有统计学差异。结论新型钛合金人工腰椎间盘符合人体力学要求。

    Abstract:

    Objective Design a new kind of titanium alloy artificial lumbar intervertebral disc and evaluate its biomechanical features.Methods The new designed artificial lumbar intervertebral disc with ball and socket joint was made of new titanium alloy with low stiffness(50GPa).The tests for compressive stiffness,torsional stiffness and fatigue strength of the artificial disc were made by the material testing machine.Results The new artificial lumbar intervertebral disc has had the functions for flexion,extension,lateral bending when tested with the mechanical tests to show its compressive stiffness as 50~66.7GPa,which is 1/3 of stainless steel.And its torsion stiffness is 388.54Nm/°.No obvious damage appeared after 1 07 fatigue strength tests.Compared with the stiffness before testing,it showed that 1,2,5 and 10 million cycles made no significant difference.Conclusion The new artificial lumbar intervertebral disc showed similar mechanical characteristics to that of the normal human lumbar disc.

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张勇,朱悦,郝玉琳,李述军.新型钛合金人工腰椎间盘的生物力学研究[J].医用生物力学,2008,23(5):357-360

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