目的在植入人体的下颌骨假体孔洞中填充松质骨颗粒,以考察松质骨在人体应力环境下是否能够达到骨细胞生长应力水平,使假体与人体骨能够长合。方法模拟下颌骨体部、跨中线和半侧缺损状态,设计了相应的修复假体并在其上打孔,在孔中填充松质骨颗粒,利用有限元软件(Ansys8.0)模拟分析了松质骨上的应力水平。结果考察了三种缺损假体孔洞中松质骨的应力水平,确定了松质骨骨细胞生长应力水平阈值。结论作用于假体松质骨上的应力可以达到骨细胞的生长水平,并为假体设计提供了力学参考。

Objective The cancellous marrow were implanted in the holes of the mandible prosthesis to study whether the cell bone can reach growing stress level under normal human condition. The threshold value of growing stress can combine the prosthesis and mandibular. Method Three types of defection- Central defect, Lateral defect, Hemimandible defect- were simulated in mandibular geometry model, three types of prosthesis were designed accordingly and holes were made in the prosthesis. The cancellous marrow were implanted in those holes and FE software (Ansys8.0) was used to analysis the stress level of cancellous bone. Results Stress level of Cancellous bone in three types of prothesis were studied and the threshold value of growing stress level on cancellous bone was determined. Conclusions The stress of cancellous bone implanted in the prosthesis can reach the bone cell growing level, and this can give guidance in prosthesis design.