目的对自行开发的动态机械应变细胞加载仪中的弹性底培养皿的硅橡胶膜的应力分布情况进行分析,从而明确膜上各部位细胞所处的应力环境,为进一步探讨应力对细胞生长的影响提供理论依据。方法应用三维有限元软件ANSYS8.0对硅橡胶膜加载后的应力和位移情况进行分析,根据有限元的轴对称原则进行建模,并进行边缘约束和位移加载,从而模拟硅橡胶膜接受球冠顶板的拉伸后所产生的应力变化。结果通过有限元分析得出了硅橡胶膜在牵张应变时的von Mises应力云图、位移云图及应力数值。结论1%、5%和10%应变组中,在膜的边缘区和中央区之间的环形区的应力值要低于前两个区,并且其应力值颜色无突变性。在20%和25%应变组中,中央区和环形区的应力值比较接近,但是从应力值看中央区仍稍高于环形区。

Objective To study stress distribution of silastic membrane in dynamic mechanical cell strain unit by self-developed to know about stress of cells at different location. Method 3D Finite element method analysis with software ANSYS 8.0.was made. Based on axis symmetry theory, the model with DOF constraint and displacement load was established to simulate the practical condition for the silastic membrane under the tension. Results The Von mises stress nephogram, displacement nephogram and stress value were obtained via software ANSYS. Conclusion Stress in ring-shaped area is lower than that in marginal and central area with strain of 1%, 5% and 10%. Stress in central and ring-shaped area with 20% and 25% strain looks approximately close to each other but thestress value in central area is still more than that in ring-shaped area.

上海市重点学科(特色学科)建设项目( T0202)