Mechanics regulates biological processes at the molecular, cellular, tissue, organ, and organism levels. The studies of mechanobiology encompass several broad research areas including the mechanical environment in health, disease, or injury, the mechanosensitive responses and their mechanisms, the inter-relations between mechanics and biological processes such as growth, remodeling, adaption, and repair, and the discoveries that advance therapeutic and diagnostic procedures. The recent advances in cardiovascular mechanobiology in China were presented. The researches on cardiovascular mechanobiology are a study in search of principles of stress-growth in vasculature to bring out how are mechanical factors developing biological effect resulting in vascular remodeling, and the analytical and computational models based on solid mechanics, fluid mechanics, or thermomechanics, as well as new experimental methods that expand measurement capabilities and facilitate analysis for cardiovascular clinic. These studies will have very important theoretical and practical significance for understanding the mechanical mechanism of blood circulation, the nature laws of growth and senility of vasculature, expounding pathological mechanism of cardiovascular diseases, and the research and development of new medicines and technology in cardiovascular clinic.