Objective: To investigate the biomechanical performance of a newly designed cervico-trochanteric stemless prosthesis by comparing the stres distribution with that of the traditional stem-type porous-coated anatomic prosthesis. Methods Using CT scanning photographs of real femur, three-dimensional finite element models were created for the intact, cervico-trochanteric (with two or three fixation screws), and porous-coated anatomic implanted femora with the geometry of a standardized real femur. Analysis was performed for a loading condition simulating the single-legged stance. The von Mises stress distributions of each model were analyzed and compared. Results The results can be summarized as follows: (1) Von Mises stress in the proximal, medial femur for the cervico-trochanteric implanted model was higher than that of the intact model and the porous-coated anatomic implanted model; (2) stress-shielding effect of the cervico-trochanteric models (with two or three fixation screws) were eliminated as compared with the porous-coated anatomic model; (3) no obvious difference in von Mises stress distribution for the cervico-trochanteric implanted model with two or three fixation screws. Conclusion The cervico-trochanteric femoral prosthesis may reduce the stress-shielding effect of the proximal femur and achievea more physiological stress distribution on the proximal femur than that of the porous-coated anatomic prosthesis.