Cytoskelelon biomechanics has emerged as a new field of cell mechanics. The cytoskeleton modeling is critical for investigating the transduclion and distribution of mechanical forces in cell, which is fundamental to cell function and biochemical events. Cytoskeleton is also the transduction medium of forces and biochemical signals. The applied mechanical forces control the chemical reaction and signal transduction through the interconnected aetin cyloskeletal network. In this paper, we review three major models, approachs and key accomplishments in cytoskeleton mechanics from a mechanical point.