颈椎前路椎体间微创融合器的生物力学实验研究
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江苏省科技厅社会发展项目(BS2003041)


Biomechanical study on new minimally embedded invasive cervical fusion cage
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    摘要:

    目的评价植入镍钛记忆合金微创融合器(NiTi-TFC/C)的颈椎节段的稳定性及压缩力学性能。方法采集24只羊颈椎标本随机分为4组,每组6份,四组处理分别为:单取髓核组、自体髂骨植骨组、微创融合器组和钛制融合器组(InterFix)。所有标本进行前路减压,并对后3组进行椎间融合术。分别对各组标本进行生物力学测试并进行比较。结果微创融合器组与钛制融合器组在强度、刚度及扭转力学等方面无显著性差异(P>0.05)。而微创融合器组与自体髂骨植骨组具有显著性差异(P<0.05)。最大承载力为12050N。结论该微创融合器强度大、刚度高、抗扭转能力强,具有良好的抗压能力,为颈椎融合提供新型的融合装置。

    Abstract:

    Objective To evaluate the stability and compressive mechanical functions of the cervical spine after implanting a new minimally embedded invasive fusion cage made of Nititanium shape memory alloy (NiTi-TFC/C). Method Anterior cervical discectomies were performed on 24 mature sheep spines which were divided randomly into four groups of six sheep cervical spines each: the discectomy group, the autogenic iliac bone graft group, the NiTi-TFC/C group, and the Inter Fix (Sofamor Danek) group. The stability of each group was tested by experimental stress analysis. Result There was no significant difference between the groups of NiTi-TFC/C and Inter Fix in the biomechanical characters (P>0.05). There was significant difference between the groups of NiTi-TFC/C and autogenic iliac bone graft (P<0.05). Conclusion NiTi-TFC/C shows effective characters with high strength and stiffness, less depression displacement. It provides a new kind of device for cervical fusion.

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庄苏阳,吴小涛,茅祖斌,洪鑫,王以进.颈椎前路椎体间微创融合器的生物力学实验研究[J].医用生物力学,2005,20(3):163-168

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