When cells are exposed by force they will have many effects of expressions. In this study we will introduce different experimental methods about cells exposed by force and different effects of expressions are studied. The article is mainly concerned with the mechanosensitive channel currents recorded in microvascular endothelial cells, ICAM-1 expression, the secretion of monocyte chemotactic protein-1,expression of proto-oncogenes c-fos and c-myc.