Objective To assess the efficiency of intra oral comprehensive anchorage on the reinforcement of stability of molar segments. Methods 15 adolescents with Class I severe anterior crowding were included for the trial. The comprehensive anchorage package, which consisted of the transpalatal arch(TPA), banding of second molars and the canine laceback, was adopted simultaneously to maintain the integrity of molar relations. Quantitative cephalometric analysis was conducted for the evaluation of the anchorage efficacy. Results Minimal mesialization of anchorage molars was verified by evaluation measurements of Ptm 6, So 6 AP ; 6 PP,MP FH and ANS Me, indicating a strong consolidation of molar anchorage.Conclusion A comprehensive employment of intra oral anchorage reinforcement comprised by TPA, second molar banding and canine laceback might lead to a sufficient resource for anchorage control.