动脉血栓形成过程的血流动力学有限元分析
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A FINITE ELEMENT ANALYSIS OF THE HEMODYNAMICS IN THE ARTERY DURING THROMBOSIS
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    摘要:

    目的:研究动脉粥样硬化或血栓形成过程中血流动力学改变,为临床治疗提供理论指导。方法:采用ANSYS V5.4有限元分析软件模拟血管建模并通过有限元分析方法观察了该模型因动脉粥样硬化斑或血栓形成所致血管逐步狭窄后血流状态的改变。同时观察了血液粘度逐步下降过程对血流状态的影响。结果:正常情况下,动脉血管内血流形式为层流,每层间血流速度不同,中心处血流速度最快,越向管壁处血流速度越慢。在血管狭窄部位则主要为高速层流,且该高速层流区流速随狭窄加重而回加快,缩窄区两端出现血液瘀滞区。血液粘度下降,高速层流区向远心端移动,缩窄区两端血液瘀滞区发生改变。结论:实验提示,临床上通过持续扩张血管的治疗有可能性改善动脉粥样硬化的治疗效果,有必要进一步研究血液粘度在该病治疗中的意义。

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    Objective:To provide a theoryetical guide for the clinical treatment, the changes of the hemodynamics during the process of the atherosclerosis spots and thrombosis were investigated. Methods: The vascular model were simulated by the ANSYS V5.4 software, and the vessel cavity were reduced progressively just as that of the artery in the atherosclarosis and thrombosis, the blood flow of the models in those conditions were analyses by the finite element method. The blood flow states in different viscositees were also observed by the method. Results: The blood flow in the normal vessels were laminar flow, the velocities were different in every stratum, the velocities were the fastest in the center and slow down towards the vessel wall. In the field where the vessel were narrowed, the dominant now were high speed laminar flow, and the speed were accelerated with the reducing of the vessels diameter. The blood flow became silted up in both side of the narrow field. When the viscocities come down, the high speed laminar flow were moved towards aistant heart side and the basis field changed. Conclution: From the study, it was suggested that through continuously ectatic treatment to the narrowed vessels, the treatment effect may be improved. It's necessary to study the meaning of the blood viscosity in the treatment of the disease.

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班兴敏,张延芳.动脉血栓形成过程的血流动力学有限元分析[J].医用生物力学,2001,16(1):44-47

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