灌注压对左心室壁心肌层间血流影响的建模与仿真研究
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A STUDY OF TIME-DEPENDENT BLOOD FLOWS AMONG MYOCARDIUN LAYER AND THEIR DEPENDENCE ON PERFUSING PRESSURE WITH MODELING AND EMULATION
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    摘要:

    为了研究心肌各层间交换血流的时相分布,建立了一个左心室壁血流灌注计算机仿真模型。心室壁分为三层,每层中的血管网用一时变阻容网络来代表。以六条雄性犬的左心室压和主动脉压的实测数据作为输入进行仿真。结果表明,用体外反搏的反搏的方法提高灌注压对心肌各层间交换血流有明显改善。

    Abstract:

    A mathematical model was proposed for the studying of the time-dependent blood flows among myocardium layers. There were three classical myocardial vascular nets in each part and each net was represented with a branch of time-dependent nonlinear resistance and compliance. Experimentally measured aortic pressure and left ventricular pressure from six male dogs were taken as input data for emulation. The results show that the blood flows among myocardium predicted with the model were increased obviously with augment of the perfusing pressure by EECP.

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王怀阳,郑振声,吴晓明,岑人经.灌注压对左心室壁心肌层间血流影响的建模与仿真研究[J].医用生物力学,2000,15(3):152-156

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