老年冠心病人脑循环动力学的改变
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全军总后卫生部科研基金


CHANGE OF CEREBRAL CIRCULATION DYNAMICS IN THE ELDER PATIENTS WITH CORONARY HEART DISEASE
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    摘要:

    目的:心脑血管疾病在当今疾病死亡率中占第一位,如何早期防治,减少死亡率,对其相应研究内容非常之多。本文侧重研究心功能基本正常的老年冠心病患者,其脑循环动力学的改变。方法:60例老年冠心病患者及68例正常对照组间的心功能参数及脑循环动力参数的比较。结果:本组冠心病患者心功能8个指标中,唯有主动脉内径减小有显著性差异外,余项均在正常范围内。但脑循环动力参数已有显著性改变。主要表现在颈内动脉最大血流速、最小血流速均减小、颈内动脉直径减小、搏动指数、阻力指数均增高。脑血管阻力、特性阻抗增高。脑血管功能已受到明显损害。提示早期防治脑血管疾病的重要性。结论:虽然老年冠心病人没有任何脑部症状和体征,但他们的脑血管功能早已发生变化。因此,对冠心病人早期防治脑血管疾患,减少脑血管疾病对病人带来的危害是十分重要的。

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    Cardiovascular and cerebrovascular diseases are in the first place of death rate at present, there are many articles on how to prevent and treat them at early stage to reduce the death rate. The study in this paper is mainly on the change of cerebral circulation dynamics in the elder patients with coronary heart disease whose ventricular function is basically normal. Methods: Taking 60 cases of elder patients with coronary heart diseases and 68 normal cases as comparative group to see the parameters of heart function and cerebral circulation dynamics parameters. Results: among & heart function indexes in coronary heart disease group, only aortic internal diameter has distinguishable reduction, other indexes are normal, but cerebral circulation dynamics parameters have distinguishable change. It mainly shows that both the maximal and minimal blood speed of carotid are reduced; carotid diameter is reduced; pulse index and resistance index are all raised; cerebrovascular and special resistance are increased; nerve self-regulation ability for cerebrovascular function and critical pressure are also all decreased. Conclusion: Though the elder patients with coronary heart disease have not got any brain symptom and sign, their cerebrovascular function has been early damaged. It shows that it is important for the elder patients with coronary heart disease to prevent cerebrovascular diseases at early stage.

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高健,王树贤,张淑文,刘玉莉,孙亚娟,乔永丽,赵燕青,丁光宏,姚伟.老年冠心病人脑循环动力学的改变[J].医用生物力学,2000,15(1):8-12

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