锥板式粘度计测量血液粘度的影响因素探讨
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A STUDY ON INFLUENTIAL FACTORS IN THE BLOOD VISCOSITY TESTING BY CONE AND PLATE VISCOMETERS
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    摘要:

    目的:对锥板式粘度计测定血液粘度的重复性及一些影响因素进行实验观察。方法:采用锥板式粘度计测定SD大鼠、金黄地鼠分别于不同温度及不同切变率下的血液粘度。结果:切变率在11.25~455s(-1)时,SD大鼠与金黄地鼠全血表观粘度随切变率的增加迅速下降,在150s(-1)以上时,两组粘度值都趋于恒定;金黄地民全血高切(225s(-1))粘度、低切(11.25s(-1))粘度在低于37℃时随温度的降低而增加,高于43℃时则随温度的升高而增加,37~43℃之间粘度随温度的变化较小,43℃的粘度则低于37℃之检测值;血浆粘度与温度变化呈负相关(r=-0.96,p=0.01);一些其它因素如测试过程中出现的血沉也对测试结果有影响。结论:使用锥板式粘度计测量血液粘度时,测量值受多种因素的影响。

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    Objective: To study the testing repeation and inf'luential factors in the blood viscosity testing with the cone and plate viscometers. Methods f Blood viscosities of SD rat and hamster were tested in different temperatures and shear rates. Results f When the shear rates were in 11.25~45s, the blood viscosities come down quickly with the increase of the shear rate, when the shear rates were higher then 150s , two of the testing values tended to be constant; When the temperatures were below 37℃, the blood viscosity of the hamster in high shear(225s ') and low shear (11.25s-1) went up with the temperatues fell, When the temperature were higher than 43oC two kinds of blood viscosity went up with the increase of temperature. When the temperatures were in 37-43℃, the changes of the blood viscosity with the temperatures were less, The changes of the plasma viscosity was negatively related to that of the temperatures (r=-0.96, p<0.01); Some other factors such as erythrocyte sedimentation in the testing couse were also affect testing values. Conclusion: The testing values teasted by the cone and plate viscometers were affected by manifold factors.

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班兴敏,吴祖明.锥板式粘度计测量血液粘度的影响因素探讨[J].医用生物力学,1999,14(1):37-40

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