兔动脉硬化时脑血管血液动力学参数变化及相关性分析
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THE CHANGES OF CEREBROVASCULAR HEMODYNAMIC PARAMETERS AND THE RELATIONAL ANALYSIS UNDER THE CONDITION OF ARTERIOSCLEROSIS IN RABBITS
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    摘要:

    本文报道了兔动脉硬化时,脑血管血液动力学参数(CVHP)的变化。动脉硬化组(AS组)颈动脉平均血流量(Qmean)、平均血流速度(Vmean)、最大血流速度(Vmax)、最小血流速度(Vmin)和脑血管零压顺应性(CO)显著降低(P<0.05~0.01),脑血管外周阻力(R)及脑血管特性阻抗(Zc)显著升高(P<0.05及0.001)。颈动脉病变程度与Qmean、Vmean和CO有显著负相关(P<005),与R和Zc有显著正相关(P<005及0.01)。Qmean与Vmean、Vmax和CO有显著正相关

    Abstract:

    In the experimental rabbit arteriosclerosis,the changes of the cerebrovascular hemodynamic parameters(CVHP) and the relationship were observed.In arteriosclerosis group(AS group). the mean flow(Qmean), Mean velocity(Vmean), Maximal velocity(Vmax) and minimal velocity(Vmin) of the carotid blood flow and cerebrovascular compiance for zero pressure(co) were significantly decreased (p<0.05,0.01), but the values of cerebrovascular peripheral resistance(R) and characteristic impedance(Zc) were significantly increased(P<0.05 and 0.01) as compared with those in control group(C group). The values of Qmean, Vmean,and CO showed siguificant negative correlation (P<0.05,0.01) but those of R and Zc showed siguificant positive correlation (P<0.01 and 0.05) with the carotid lesions.When compared the linear equations of AS group with those of C group,the regression coefficient b of Qmean-Vmax and Qmean-R showed significant difference (P<0.01 and 0.001);the intercept a of QmeanVmean,Qmean-CO and Qmean Zc showed significant diffenence (P<0.05,0.01)

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王京,史荫绵,李惜惜,柳兆荣,丁光宏.兔动脉硬化时脑血管血液动力学参数变化及相关性分析[J].医用生物力学,1996,11(2):92-96

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