Objective To investigate the dynamic response of lenke3 scoliosis finite element model. Method A finite element model was established for CT images of Lenke3 scoliosis patients, and the validity of the model was verified. Modal analysis, harmonic response analysis and transient dynamic analysis were carried out. Result The first order natural frequency of this model is only 1.2Hz; The amplitude of the finite element model is the largest at the first natural frequency. At the same resonance frequency, the amplitude of the thoracic curved vertebra was larger than that of the lumbar curved vertebra. The amplitude from T6 vertebra to L2 vertebra decreased successively. Conclusion The degree of spinal deformity may affect the perception of vibration, and the higher the degree of spinal deformity, the higher the sensitivity to vibration. The first natural frequency was most harmful to lenKE3 scoliosis patients. Under cyclic loading, the thoracic curved vertebra is more prone to deformation than the lumbar curved vertebra. The closer you get to T1, the greater the amplitude of the vibration.