优化取栓支架的力学性能研究
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上海理工大学 医疗器械与食品学院

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Study on mechanical properties of optimized stent retrievers
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    摘要:

    目的 分析不同结构的取栓支架的机械性能,为取栓支架的设计以及临床选择提供理论支持。方法 通过有限元分析以及体外模拟实验对三款不同结构的取栓支架(B3、K4、X)进行评估,分析指标是径向支撑力、回撤力以及模拟取栓过程中的血栓状态。结果 实验得到的三款取栓支架的径向支撑力分别为B3(0.48N)、K4(0.43N)、X(0.51N),且压握程度越大,取栓支架的径向支撑力越大;当压握距离大于3mm时,支架的径向支撑力显著增大。模拟取栓实验结果表明,三款支架的回撤力峰值分别为B3(0.410N)、K4(0.451N)、X(0.501N),实验结果与有限元分析的结果具有趋势一致性。结论 实验结果与有限元结果均表明,X支架具有更好的力学性能,此方法可作为评估取栓支架性能的一种分析方法,为取栓支架的性能提高和研发提供一些参考。

    Abstract:

    Objective To analyze the mechanical properties of stent retrievers with different structures and to provide theoretical support for the design and clinical selection of stent retrievers. Methods Three kinds of stent retrievers with different structures (B3, K4, X) were evaluated by finite element analyses and in vitro simulation experiment. The analysis parameters were radial support force, withdrawal force and the thrombosis state during the thrombotomy test. Results The radial supporting forces of the three stent retrievers obtained from the experiment were B3(0.48N), K4(0.43N), X(0.51N), respectively. The larger the crimping size, the greater the radial supporting force of the stent retrievers. The radial support force of the stent increases significantly when the crimping size is larger than 3mm. The simulated thrombus removal experiment results show that the peak values of the three stent are B3(0.410N)<K4(0.451N)<X(0.501N). The experimental results are consistent with the results of finite element analysis. Conclusion Both the experimental results and the finite element results show that the X stent has better mechanical properties. This method can be used as an analysis method to evaluate the performance of the stent retrievers, and provide some references for the performance improvement and development of the stent retrievers.

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  • 收稿日期:2021-06-11
  • 最后修改日期:2021-07-20
  • 录用日期:2021-07-22
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