目的 建立山羊颈椎不稳定模型，测试新型弧形带终板环的颈椎钛网的生物力学稳定性。方法 测量成年贵州白山羊颈椎的解剖学数据，以选择适合山羊颈椎的新型弧形带终板环的颈椎钛网。将保留了关节囊、韧带及椎间盘的24只山羊颈椎骨性标本随机分成4组：A组（n=6）为正常组，B组（n=6）为模型组，C组（n=6）实验组，D组（n=6）对照组。A组无特殊处理，B组切除C4部分椎体及上下椎间盘，C组在B组基础上安装新型弧形带终板环的颈椎钛网并予钢板螺钉辅助固定，D组在B组基础上安装传统直行钛网并予钢板螺钉辅助固定。使用美国魔神步态分析系统测量4组标本在2.0NM载荷下前屈、左右侧弯、左右旋转、后伸六种活动的ROM，测试其三维运动稳定性。利用美国BOSE公司轴向压缩实验机器测量C、D两组在200N压缩力矩下的位移，计算其刚度，测试其抗沉降能力。采取方差分析的方法，比较四组的ROM及C组与D组刚度的差异。结果 A组各方向活动范围均小于B组，差异存在统计学方面意义（P＜0.05）；A组各方向运动范围均大于C组，差异存在统计学方面意义（P＜0.05）；C组在前屈运动范围上小于较D组，差异存在统计学方面意义（P＜0.05）；C组的刚度较D组高，差异存在统计学方面意义（P＜0.05）。结论 新型弧形钛网较直行钛网更加符合颈椎生理曲度，在颈椎最频繁的前屈活动上稳定性较直行好，且短期应力下抗沉降较直行钛网好，值得进一步实验及临床推广。
Objective The instability model of goat cervical vertebra was established, and the biomechanical stability of the new curved cervical titanium mesh with endplate ring was tested. Methods The anatomical data of the cervical vertebrae of adult Guizhou white goats were measured in order to select a new type of curved cervical titanium mesh with endplate ring which is suitable for the cervical vertebrae of Guizhou white goats. Twenty-four goats with preserved articular capsule, ligament and intervertebral disc were randomly divided into four groups: group A (n = 6) as normal group, group B (n = 6) as model group, group C (n = 6) as experimental group and group D (n = 6) as control group. There was no special treatment in group A, partial resection of C4 vertebrae and upper and lower intervertebral disc in group B, cervical titanium mesh with endplate ring in group C and plate and screw fixation in group B, and traditional straight titanium mesh in group B and plate and screw assisted fixation in group D. The American magic gait analysis system was used to measure the ROM, of four groups of specimens: flexion, extension, left and right lateral bending and left and right rotation under 2.0NM load to test their three-dimensional motion stability. The axial compression test machine of BOSE Company was used to measure the displacement of C and D groups under 200N compression torque, calculate their stiffness and test their anti-settlement ability. The ROM of group An and group B, group An and group C, group C and group D and the difference of stiffness between group C and group D were compared by the method of analysis of variance. Results The range of movement in all directions in group A was smaller than that in group B, and the difference is meaningful (P < 0.05); The range of movement in all directions in group A was larger than that in group C, and the difference is meaningful (P < 0.05). The range of flexion movement in group C was smaller than that in group D, and the difference is meaningful (P < 0.05). The stiffness of group C was higher than that of group D, and the difference is meaningful (P < 0.05).Conclusion The new type of arc titanium mesh is more consistent with the physiological curvature of the cervical spine than the straight titanium mesh, and has better stability in the most frequent cervical flexion activities than the straight mesh, which is worthy of further experiment and clinical promotion.