目的 研究基于weaire-phelan结构支架（LWP）的力学性能，并利用有限元分析（FEA）方法精确模拟多孔支架的整个压缩过程。方法 采用选择性激光熔融（Selective Laser Melting，SLM）技术制造具有不同孔隙率的Ti6Al4V（TC4）多孔支架。通过单轴压缩试验测试样件的力学属性，并与人体骨骼及其他支架结构进行对比。验证四种材料模型对多孔支架压缩仿真结果的影响。结果 LWP支架展现出与人体松质骨十分接近的弹性模量以及高于大多数皮质骨的屈服强度。与其他支架结构相比，LWP支架具有几乎最小的弹性模量和最大的屈服强度。利用本文提出的材料模型，即Johnson-Cook本构模型和动态几何应变失效模型（JCDG），模拟出的结果与试验数据非常接近。结论 作为骨修复材料，LWP支架展现出比其他支架结构更优秀的力学性能。与其他材料模型相比，JCDG更有利于构建出合理的多孔支架压缩仿真模型。
Objective To study the mechanical performance of porous scaffolds with lattice Weaire-Phelan (LWP) structure and simulate the whole process of compression test precisely using finite element analysis (FEA) method. Methods The Ti6Al4V (TC4) porous scaffolds with different porosity were manufactured by selective laser melting (SLM) and measured by uniaxial compressive tests to obtain their mechanical properties, which would be compared with that of human bones and the porous scaffolds with other cellular structures. Four types of material models were verified for their effect on the simulation of porous scaffold compression. Results LWP samples presented the elastic modulus close to that of human cancellous bone and significantly higher yield strength than that of cortical bone in most parts of human body. As opposed to the biomaterial with other porous structures, LWP samples exhibited lower elastic modulus and higher yield strength. The simulated results derived from the material model developed in this study, namely, Johnson-Cook constitutive model and failure model based on dynamic geometric strain (JCDG), were proved very consistent with the experimental data. Conclusions LWP scaffolds as the bone repair biomaterial exhibited more excellent mechanical performance than the biomaterial with other porous structures. JCDG was more beneficial for establishing the reasonable simulation model of porous scaffold compression, compared with other reported material models.