The method of biomechanical modeling and computer simulation for human movement has been widely used in such research fields as elucidating physiological mechanisms of different kinds of movements, investigating the causes of sports injuries, helping to promote sports performances and to prevent injuries for athletes. Such method involves mathematical modeling on a series of physiological, anatomical and mechanical characteristics of human bones, joints, muscles and nerves. Muscle forces exerted during movements can be estimated using algorithms based on such models. Meanwhile, simulation experiments can be performed and make the results visualized by using computer software. This paper will review the biomechanical modeling and computer simulation of human movement and its application in details.