目的 通过数值计算判断血流动力学特性的突变对双分叉动脉血管病变发展的影响。方法 利用边界元方法计算了一类双分叉侧支型动脉血管主支管病变前后的血液流场、血管壁切应力、压力等血液流体动力学特性，并作了分析和比较，对病变产生、发展和加剧的流体动力学原因做出了合理的解释;通过对病变前后分支管壁切应力和压力的计算结果分析,对主支管的病变是否会影响分支管的血液流体动力学特性做出了判断。结果 主支管病变处由于血管腔变窄血液流速明显变大、切应力变大，主支管病变或病变加剧对分支管血液流场分布及切应力并无明显影响，而使分支管壁血压升高。结论 血液的流体动力学特性对动脉粥样斑块的形成、发展、加剧、破裂有一定的影响，双分叉动脉主支管病变的加重极易导致分支管分叉处粥样斑块病变的出现。

Objective To judge the effect of hemodynamic characteristics on flow vessel of double bifurcation collateral by numerical calculation. Method A kind of double bifurcation collateral flow vessel’s hemodynamic characteristics such as blood flowing velocity vector, the shear stress and pressure at the vessel wall were calculated, studied and compared by the boundary element method. The lesions caused and developed by hemodynamic reasons were logically explained. Whether the hemodynamic characteristics of the branch would be affected by the lesion in the primary branch vessel was judged based on calculation results of the shear stress and the pressure at the branch vessel wall before and after the lesions. Results In the primary branch vessel, the blood velocity and shear stress increased obviously if the lesion appeared to narrow the vessel. Although the blood velocity and the shear stress in the branch vessel were not affected by the lesion, but its blood pressure became high. Conclusions The blood hydrokinetic characteristics play an important role in the cause and development of cardiovascular diseases. The atherosclerosis could be caused in the branch vessel of double bifurcation arterialvessel as the lesion becomes more serious in its primary branch vessel.

内蒙古民族大学科研项目(MDX2008106)，内蒙古民族大学创新团队建设计划项目