Objectives: In order to provide the scientific base for clinical application of multi - function femoral plate(MFFP), we studied the MFFP system on supracodylar fracture and intercondylar fracture of femur and we compared the advantages and disadvantages of the different kinds of internal fixations to the MFFP system. Methods: Twelve femoral condyles of fresh cadaver were measured and analysed the biomechanical performances of the MFFP system and the other internal fixations. Results: The results show that the MFFP system is prior to dynamic condylar screw, L-steel plate and the other internal fixations, because the stress and the strength of the MFFP system is more different than the others. The experimental and theoretical results show that the stress of intercondylar process become bigger, the stress of femoral shaft become greater and the separate displacement of intercondyle become smaller. Conclusions: The MFFP system has following advantages. It has proper design, fitting humans biomechanical performances effctive ability on the anti-rotation and being easy to insert. The MFFP system was used on twelve supracodylar fracture and intercondylar fracture of femur. The result was shoued that the ratio escellent and good results was 96.8% and that all cases were cured and no complication. The result was showed that MFFP system oh supracodylar fracture and intercondylar fracture of femur was an excellent internal fixation. Therefore, it is worth popularizing.