金黄地鼠和SD大鼠全血Casson粘度和Casson屈服应力
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CASSON VISCOSITY AND CASSON YIELD STRESS IN THE BLOOD OF HAMSTER AND THE SD RATS
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    摘要:

    用一元线性回归得出金黄地鼠和SD大鼠全血Casson粘度(CV)和Casson屈服应力(CY)。结果表明:金黄地鼠和SD大鼠的CV值无明显差异(p>005),CY值差异显著(p<0.01)。提示:在疾病、药物等有关红细胞变形性的研究中可选择金黄地鼠和SD大鼠作为实验动物模型,两者无差异;而在研究红细胞聚集性显著的实验中选择SD大鼠较好,不显著选择金黄地鼠较好。在血液流变学研究中普及和推广应用CV和CY具有重要意义。

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    Values of the Casson Viscosity (CV) and Casson yield stress(CY) in the blood of hamsters and SDrats were obtained by unitary linearly regression. Results : There was not significantly difference inthe CV value between hamsters and rats (p>0.05). Significantly difference was found in the CYvalue (p<0.01). The results suggests that : in the study of the erythrocyte deformabllity propertiesabout diseases and medicines, hamster as well as rats can be act as a good animal model, but in thestudies which have significantly erythrocyte assemble properties, it's better to choose SD rats. Iferythrocyte assemble property is not significant, the hamster may be a better choice. It has animportant significance to popularize and spread the CV and CY in the hemorheology study.

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张延芳,班兴敏.金黄地鼠和SD大鼠全血Casson粘度和Casson屈服应力[J].医用生物力学,1999,14(3):163-165

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