高血压鼠和正常鼠血管的生物力学特性
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

基金项目:


THE VESSCLE'S BIOMECHANICS OF SHR AND WKY
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    本文就原发性高血压大白鼠(SHR)和正常京都纯种大白鼠(WKY)作对照,测定其胸主动脉的管径、厚度、应力-应变和断裂时的相对伸长度,在拉格郎日(Lagrangian)意义下讨论应力应变,并按冯元桢-维拉伸理论,从实验得出经验公式:dT/dλ=α(T-β)=αT-E0,以确定高血压和老龄化血管生物力学性能的变化。发现:不仅京都鼠血管的相对伸长率大于高血压鼠,而且从各年龄观察,幼龄的血管相对伸长率大于老龄者,高血压和老龄者的血管弹性模量相对大;在低应力区时,高血压和老龄化的胸主动脉弹性差,弹性模量大,刚度大;

    Abstract:

    We tested the thoracic aortas of spontaneously hypertensive rats(SHR)and Wistar Kyoto Rats(WKY)about diameter,thickness,strain-stress and relatively stretch length at fragility time.According to Lagrangian meaning and straight stretch theory of Feng Yuanzhen, we discussed the strain-stross and got the experience fomula:dT/dλ=α(T+β)=αT+ E0,which was used to assess the vascula's boimechanics of SHR and WKY in hypertension and aging.It is show that not only the vesscle's relatively stretch length of WKY is more than SHR'S, but also young than old(P<0.01,P<0.05).The vasculas of SHR and aging have higher elastic modulus.Always,the elastic protein and smooth muscle play an important role at the lower strain and the collagen fiber at higher strain.It is considered that the thoracic aortas in SHR and aging having higher elastic modulus are due to the decline in elastic protein.

    参考文献
    相似文献
    引证文献
引用本文

徐丹令,沈金根.高血压鼠和正常鼠血管的生物力学特性[J].医用生物力学,1996,11(3):163-166

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期:
  • 出版日期:
文章二维码
关闭