The measuring of the 3-D mechanical properties of the small artery is significant for the investigation and clinical diagnosis of vascular surgery and evaluation of treatment efficiency.In order to describe the performance of the artery blood vessel.On the basis of anisotropic and nonlinear behavior of the blood vessel,the author applied biomechanical principle to set up a three dimensional constitutive equation of small artery blood vessel.Going through the mechanical analysis,examination,and statistics,the accuracy and reliability of the data of small artery was defined.Thus,a dependable data was provided building up the model of parameters.